AI Engineering Roles · St. Louis, MO
AI Engineering Roles salary in St. Louis.
321 roles tracked. Median $119,700. 10% below national.
$30,600
Low
$119,700
Median
$312,300
High
St. Louis offers one of the most affordable major metro areas in the country, with a strong base in healthcare, financial services, and manufacturing. The region's anchor employers include Boeing, Centene, and Washington University's medical campus. A growing biotech and plant sciences corridor centered on the Cortex Innovation District is attracting new investment and talent.
Missouri's top income tax rate is about 4.8%, and St. Louis City adds a 1% earnings tax. The low base cost of living means your after tax salary still stretches further than in most metros.
Emphasize your willingness to work in person at Cortex or the BJC campus. St. Louis employers offer higher packages for candidates who commit to the local innovation hubs.
AI Engineering Roles ranked by pay in St. Louis.
Salaries adjusted for St. Louis cost of living (-10% vs. national). Click any role for the full role-city breakdown including equity, bonuses, and city-specific negotiation tips.
Common questions.
The median salary across 321 ai engineering roles tracked in St. Louis, MO is $119,700. The full range runs from $30,600 at the entry level for the lowest-paying tracked role up to $312,300 at the top of the highest-paying tracked role. St. Louis sits 10% below the national average for cost-adjusted compensation.
Machine Learning Director is the highest-paying ai engineering role in St. Louis, with a median base salary of $240,300 when adjusted for local cost of living. Total compensation including equity and bonuses runs significantly higher at top-tier employers.
Yes. St. Louis is one of the active markets for AI talent in 2026. St. AI Engineering Roles specifically benefit from local employer demand and the broader AI hiring boom that has pushed compensation up year over year.
St. Louis pays roughly 10% less than the national average for ai engineering roles. Top markets like San Francisco, New York, and Seattle typically pay 30-50% above national. Mid-cost metros like Austin, Denver, and Raleigh pay closer to national.
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