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  1. Home/
  2. Orbyt Jobs/
  3. Salary Data/
  4. Drug Discovery AI Researcher/
  5. Boston
Salaries

Drug Discovery AI Researcher.

Boston.

$265,000

median salary, 23% above the national average

$207,000 to $345,000. Last updated August 2026.

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Data points to own the conversation.

A Drug Discovery AI Researcher in Boston earns a median of $265,000 in 2026. That is 23% above the national average. The range runs from $207,000 to $345,000, and where you land depends on your experience, your skills, and how well you negotiate. The gap between theoretical knowledge and production deployment experience is the single largest salary differentiator. These figures are Orbyt estimates, computed rather than measured, and must not be cited as Bureau of Labor Statistics figures; the published BLS wage for the occupation this role maps to is shown separately on this page.

Salary range.

25th Percentile

$207,000

per year

Median

$265,000

per year

75th Percentile

$345,000

per year

Where do you fall?

$207,000$345,000

Orbyt estimate for Drug Discovery AI Researcher in Boston, modelled from national occupation wages adjusted for local cost of living. The published government benchmark for this occupation is below.

Government benchmark for this occupation

The US Bureau of Labor Statistics reports a median annual wage of $129,500 for Medical Scientists, Except Epidemiologists (SOC 19-1042) in the Boston-Cambridge-Newton, MA-NH metropolitan area, based on 16,060 employed workers (May 2025 release).

10th percentile

$77,770

25th percentile

$97,520

Median

$129,500

75th percentile

$168,020

90th percentile

$209,520

Workers surveyed

16,060

Why this differs from the estimate above. The Orbyt estimate of $265,000 is 105% higher than this published figure. That is usually not an error in either number: BLS reports by occupation code, and Medical Scientists, Except Epidemiologists covers a different population than the Drug Discovery AI Researcher title as it is typically advertised. Both are shown, unreconciled, so you can judge which one describes the job you mean.

BLS publishes wages by occupation code, not by job title, so this figure covers every role mapped to Medical Scientists, Except Epidemiologists (SOC 19-1042) rather than Drug Discovery AI Researcher specifically. The Bostonrange at the top of this page is Orbyt’s role-level estimate, which is a different thing and is labelled as such.

View the BLS source for SOC 19-1042

Salary by experience.

The gap between entry and lead level is typically $239,000. Where you land depends on years of experience and what you bring to the table.

Entry (0-2 yrs)

$172,000

to $212,000

Mid (3-5 yrs)

$225,000

to $278,000

Senior (6-9 yrs)

$292,000

to $345,000

Lead (10+ yrs)

$331,000

to $411,000

Total compensation.

Base salary is not the full picture. Equity, bonus, and signing can add $58,000 to the total package.

Base

$265,000

Equity

$32,000

Bonus

$21,000

Signing

$5,000

Estimated total: $323,000

How Boston compares.

Boston, MA

$265,000

Cost of living: 22% above average

National Average

$215,000

Boston is $50,000 above

Drug Discovery AI Researcher salary by city.

Drug Discovery AI Researcher salary comparison across 10 cities
CityMedianRangeCOLAdjusted
San Jose, CA$306,000$239,000 to $398,0001.38x$222,000
Honolulu, HI$288,000$225,000 to $375,0001.30x$222,000
New York, NY$286,000$224,000 to $373,0001.28x$223,000
San Francisco, CA$284,000$222,000 to $370,0001.35x$210,000
Washington DC, DC$269,000$210,000 to $350,0001.25x$215,000
Boston, MA$265,000$207,000 to $345,0001.22x$217,000
Seattle, WA$261,000$204,000 to $340,0001.24x$210,000
Los Angeles, CA$256,000$200,000 to $334,0001.18x$217,000
Anchorage, AK$250,000$196,000 to $326,0001.13x$221,000
Newark, NJ$246,000$192,000 to $320,0001.18x$208,000

See all 81 cities for Drug Discovery AI Researcher →

Salary by role in Boston.

Salary comparison by role in Boston
RoleMedianRange
CTO$381,000$297,000 to $495,000
CEO$346,000$251,000 to $478,000
General Counsel$345,000$269,000 to $449,000
AI Protein Structure Specialist$271,000$212,000 to $352,000
E6 Engineer$266,000$233,000 to $313,000
Drug Discovery AI Researcher$265,000$207,000 to $345,000
Healthcare AI Researcher$259,000$202,000 to $336,000
EV Battery AI Optimization Engineer$258,000$201,000 to $336,000

What you should know.

Here is what the Drug Discovery AI Researcher market actually looks like in Boston. Boston's job market is powered by world class universities, a thriving biotech corridor, and established finance and healthcare sectors. The Kendall Square area is one of the most concentrated biotech hubs globally. Tech salaries in Boston are competitive with West Coast markets, particularly for roles that intersect with life sciences, AI, and robotics. The gap between theoretical knowledge and production deployment experience is the single largest salary differentiator. Drug Discovery AI Researchers who can optimize inference costs, reduce model latency, and handle scale reliably earn significantly more. Published research or open source contributions to widely adopted frameworks create additional leverage in negotiations.

Entry-level Drug Discovery AI Researchers start near $168,000. Mid-career professionals with three to five years of experience reach $215,000 to $280,000. Senior-level roles command $275,000 to $333,000. Management transitions to director-level positions offer $355,000 and above. In Boston, those numbers run higher. The cost of living here is 22% above average, and employers adjust to compete.

Base salary is not the full picture. Equity at top-tier companies adds 30% to 60% above base salary. Annual bonuses of 15% to 25% are standard. Signing bonuses of $25,000 to $75,000 are common when changing roles. Refresher equity grants vest annually. Relocation packages and executive benefits like financial planning are typical. And on the tax side: massachusetts has a flat 5% income tax on most earnings, plus a 4% surtax on income above $1 million. There is no city income tax in Boston, keeping the total burden moderate. When someone quotes you $265,000, ask what the total package looks like. The gap between base and total comp is where real money hides.

On negotiation: Emphasize specialized credentials or advanced degrees. Boston employers, especially in biotech and finance, place a premium on educational pedigree and certifications. The range for Drug Discovery AI Researchers in Boston runs from $207,000 to $345,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.

Sources: BLS OES, H-1B LCA (DOL). COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified July 1, 2026. Full methodology

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Enter your Drug Discovery AI Researcher offer to see where you stand in Boston.

$

25th

$207,000

Median

$265,000

75th

$345,000

Considering a related role?

  • An E6 Engineer in Boston earns $266,000 (0% more)
  • The highest-paying role in Boston is CTO at $381,000
  • See all ai healthcare roles tracked in Orbyt Intelligence

Common questions.

Production deployment experience, published research or open source contributions, and expertise with the latest model architectures command the highest premiums. Proficiency in Python, PyTorch, and cloud ML platforms is baseline. Experience with LLM fine-tuning, RLHF, and inference optimization is increasingly differentiated.

AI labs and foundation model companies pay 20% to 40% more than enterprises. Well-funded AI startups offer competitive base salaries with significant equity upside. Large tech companies provide the most stable total compensation packages with strong equity vesting schedules.

It depends on the position and employer. Many Drug Discovery AI Researchers in Boston are classified as exempt salaried employees without overtime eligibility. However, equity at top-tier companies adds 30% to 60% above base salary. When evaluating the $207,000 to $345,000 range, ask about the total compensation structure during negotiation.

The national median for a Drug Discovery AI Researcher is $217,213. In Boston, cost of living adjustments push the median to $265,000. That premium reflects Boston's higher housing, transportation, and everyday costs.

Boston's cost of living multiplier is 1.22x the national average. The adjusted median Drug Discovery AI Researcher salary of $265,000 accounts for this. In practice, a Drug Discovery AI Researcher earning $265,000 in Boston has roughly the same purchasing power as someone earning $217,213 in an average cost market.

Drug Discovery AI Researcher salary in other cities.

Los Angeles$256,000
Little Rock$176,000
Louisville$184,000
Las Vegas$206,000
Miami$238,000
Minneapolis$235,000

Other salaries in Boston.

GEO/AEO Specialist$93,000
Game Designer$102,000
Green Building Consultant$99,000
Geospatial Analyst / GIS$91,000

Related salary pages

Jump to nearby roles and cities most relevant to Drug Discovery AI Researchers in Boston.

  • GEO/AEO SpecialistBoston, MA$93,000
  • Game DesignerBoston, MA$102,000
  • Drug Discovery AI ResearcherLos Angeles, CA$256,000
  • Drug Discovery AI ResearcherLittle Rock, AR$176,000
  • GEO/AEO SpecialistLos Angeles, CA$93,000
  • Game DesignerLittle Rock, AR$65,000
  • Drug Discovery AI ResearcherLouisville, KY$184,000
  • Green Building ConsultantBoston, MA$99,000

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"Drug Discovery AI Researcher Salary in Boston, MA." Orbyt Salary Explorer, August 2026. https://www.orbytlabs.ai/orbyt-jobs/salaries/drug-discovery-ai-researcher/boston

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