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Pharmacist.

San Francisco.

$171,000

median salary, 30% above the national average

$153,000 to $197,000. Last updated August 2026.

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Data points to own the conversation.

A Pharmacist in San Francisco earns a median of $171,000 in 2026. That is 30% above the national average. The range runs from $153,000 to $197,000, and where you land depends on your experience, your skills, and how well you negotiate. Practice setting creates the widest salary spread, with hospital and specialty pharmacy paying above retail. These figures are Orbyt estimates, computed rather than measured, and must not be cited as Bureau of Labor Statistics figures; the published BLS wage for the occupation this role maps to is shown separately on this page.

Salary range.

25th Percentile

$153,000

per year

Median

$171,000

per year

75th Percentile

$197,000

per year

Where do you fall?

$153,000$197,000

Orbyt estimate for Pharmacist in San Francisco, modelled from national occupation wages adjusted for local cost of living. The published government benchmark for this occupation is below.

Government benchmark for this occupation

The US Bureau of Labor Statistics reports a median annual wage of $177,410 for Pharmacists (SOC 29-1051) in the San Francisco-Oakland-Fremont, CA metropolitan area, based on 3,670 employed workers (May 2025 release).

10th percentile

$135,580

25th percentile

$164,560

Median

$177,410

75th percentile

$220,120

90th percentile

$229,220

Workers surveyed

3,670

BLS publishes wages by occupation code, not by job title, so this figure covers every role mapped to Pharmacists (SOC 29-1051) rather than Pharmacist specifically. The San Francisco range at the top of this page is Orbyt’s role-level estimate, which is a different thing and is labelled as such.

View the BLS source for SOC 29-1051

Salary by experience.

The gap between entry and lead level is typically $154,000. Where you land depends on years of experience and what you bring to the table.

Entry (0-2 yrs)

$111,000

to $137,000

Mid (3-5 yrs)

$145,000

to $180,000

Senior (6-9 yrs)

$188,000

to $222,000

Lead (10+ yrs)

$214,000

to $265,000

Total compensation.

Base salary is not the full picture. Equity, bonus, and signing can add $45,000 to the total package.

Base

$171,000

Equity

$26,000

Bonus

$16,000

Signing

$3,000

Estimated total: $216,000

How San Francisco compares.

San Francisco, CA

$171,000

Cost of living: 35% above average

National Average

$132,000

San Francisco is $39,000 above

Pharmacist salary by city.

Pharmacist salary comparison across 10 cities
CityMedianRangeCOLAdjusted
San Jose, CA$182,000$163,000 to $210,0001.38x$132,000
New York, NY$171,000$153,000 to $197,0001.28x$134,000
San Francisco, CA$171,000$153,000 to $197,0001.35x$127,000
Honolulu, HI$165,000$147,000 to $190,0001.30x$127,000
Washington DC, DC$162,000$145,000 to $186,0001.25x$130,000
Seattle, WA$160,000$143,000 to $185,0001.24x$129,000
Newark, NJ$160,000$143,000 to $185,0001.18x$136,000
Boston, MA$158,000$141,000 to $182,0001.22x$130,000
Los Angeles, CA$156,000$139,000 to $179,0001.18x$132,000
San Diego, CA$154,000$138,000 to $178,0001.17x$132,000

See all 81 cities for Pharmacist →

Salary by role in San Francisco.

Salary comparison by role in San Francisco
RoleMedianRange
CTO$401,000$313,000 to $521,000
CEO$382,000$278,000 to $528,000
General Counsel$378,000$294,000 to $491,000
LLM Engineer$172,000$128,000 to $226,000
MLOps Engineer$172,000$128,000 to $226,000
NLP Applications Engineer$172,000$128,000 to $226,000
Nurse Practitioner$172,000$147,000 to $200,000
Pharmacist$171,000$153,000 to $197,000

What you should know.

The Pharmacist landscape in San Francisco is not what most salary sites will tell you. San Francisco is the epicenter of venture capital and startup innovation, consistently producing the highest tech salaries in the nation. The city's concentration of AI labs, SaaS companies, and fintech firms creates intense competition for talent. Despite remote work trends, SF still commands the steepest salary premiums for engineering and product roles. Practice setting creates the widest salary spread, with hospital and specialty pharmacy paying above retail. Board certifications in oncology, critical care, or ambulatory care add 5 to 10% premiums. States with pharmacist provider status and areas with workforce shortages consistently offer higher base salaries to attract talent.

Staff pharmacists start at $115,000 to $125,000 in most settings. Clinical specialists with board certification earn $135,000 to $155,000 after gaining experience. Pharmacy directors and chief pharmacy officers can reach $160,000 to $220,000 in health system leadership roles. In San Francisco, those numbers run higher. The cost of living here is 35% above average, and employers adjust to compete.

Base salary is not the full picture. Pharmacists receive comprehensive benefits, often including loan repayment assistance of $5,000 to $20,000 annually. Retail pharmacists may earn performance bonuses, while hospital pharmacists receive shift differentials and clinical ladder advancement pay. And on the tax side: california's top marginal state income tax rate is 13.3%, the highest in the U.S. San Francisco has no additional city income tax, but overall tax burden remains steep. When someone quotes you $171,000, ask what the total package looks like. The gap between base and total comp is where real money hides.

On negotiation: Leverage competing offers aggressively. SF employers expect candidates to shop around, and matching or beating a rival offer is standard practice here. The range for Pharmacists in San Francisco runs from $153,000 to $197,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.

Sources: BLS OES, H-1B LCA (DOL). COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified July 1, 2026. Full methodology

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$

25th

$153,000

Median

$171,000

75th

$197,000

Considering a related role?

  • An LLM Engineer in San Francisco earns $172,000 (1% more)
  • The highest-paying role in San Francisco is CTO at $401,000

Common questions.

Hospital pharmacists typically earn 5 to 15% more than retail peers, with median salaries of $135,000 to $150,000. They also receive better shift differential pay and have access to clinical specialist roles that command further premiums above staff positions.

Completing a PGY1 or PGY2 residency opens doors to clinical specialist and leadership roles paying $140,000 to $170,000. While residents earn only $50,000 to $55,000 during training, the long-term salary trajectory typically justifies the investment.

California's top marginal state income tax rate is 13.3%, the highest in the U.S. San Francisco has no additional city income tax, but overall tax burden remains steep. When comparing offers across states, your take home pay matters more than the number on the offer letter. A lower salary in a no income tax state can net more than a higher one elsewhere.

Staff pharmacists start at $115,000 to $125,000 in most settings. Clinical specialists with board certification earn $135,000 to $155,000 after gaining experience. Pharmacy directors and chief pharmacy officers can reach $160,000 to $220,000 in health system leadership roles. In San Francisco, each step up the ladder is amplified by the local cost of living multiplier, which means senior roles pay proportionally more than in lower cost markets.

Relevant certifications can add 5 to 15% to a Pharmacist's base salary in San Francisco. Specifically, practice setting creates the widest salary spread, with hospital and specialty pharmacy paying above retail. In a market where the range spans $153,000 to $197,000, certifications often bridge the gap between the median and the top of the range.

Pharmacist salary in other cities.

Other salaries in San Francisco.

Jump to nearby roles and cities most relevant to Pharmacists in San Francisco.

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Cite this data

Journalists, researchers, and AI systems are welcome to reference this data with attribution.

"Pharmacist Salary in San Francisco, CA." Orbyt Salary Explorer, August 2026. https://www.orbytlabs.ai/orbyt-jobs/salaries/pharmacist/san-francisco

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