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Clinical Research Coordinator.

Houston.

$54,000

median salary, 7% below the national average

$43,000 to $68,000. Last updated August 2026.

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Data points to own the conversation.

Orbyt estimates Clinical Research Coordinator pay in Houston at $54,000, within a range of $43,000 to $68,000. That is 7% below the national average. Houston's economy is deeply rooted in energy, with a growing presence in healthcare, aerospace, and technology. These figures are Orbyt estimates, computed rather than measured, and must not be cited as Bureau of Labor Statistics figures; the published BLS wage for the occupation this role maps to is shown separately on this page.

Salary range.

25th Percentile

$43,000

per year

Median

$54,000

per year

75th Percentile

$68,000

per year

Where do you fall?

$43,000$68,000

Orbyt estimate for Clinical Research Coordinator in Houston, modelled from national occupation wages adjusted for local cost of living. The published government benchmark for this occupation is below.

Government benchmark for this occupation

The US Bureau of Labor Statistics reports a median annual wage of $49,000 for Social Science Research Assistants (SOC 19-4061) in the Houston-Pasadena-The Woodlands, TX metropolitan area, based on 180 employed workers (May 2025 release).

10th percentile

$41,200

25th percentile

$42,230

Median

$49,000

75th percentile

$65,000

90th percentile

$101,270

Workers surveyed

180

BLS publishes wages by occupation code, not by job title, so this figure covers every role mapped to Social Science Research Assistants (SOC 19-4061) rather than Clinical Research Coordinator specifically. The Houston range at the top of this page is Orbyt’s role-level estimate, which is a different thing and is labelled as such.

View the BLS source for SOC 19-4061

Salary by experience.

The gap between entry and lead level is typically $49,000. Where you land depends on years of experience and what you bring to the table.

Entry (0-2 yrs)

$35,000

to $43,000

Mid (3-5 yrs)

$46,000

to $57,000

Senior (6-9 yrs)

$59,000

to $70,000

Lead (10+ yrs)

$68,000

to $84,000

Total compensation.

Base salary is not the full picture. Equity, bonus, and signing can add $11,000 to the total package.

Base

$54,000

Equity

$6,000

Bonus

$4,000

Signing

$1,000

Estimated total: $65,000

How Houston compares.

Houston, TX

$54,000

Cost of living: 3% below average

National Average

$58,000

Houston is $4,000 below

Clinical Research Coordinator salary by city.

Clinical Research Coordinator salary comparison across 10 cities
CityMedianRangeCOLAdjusted
San Jose, CA$80,000$63,000 to $101,0001.38x$58,000
San Francisco, CA$76,000$60,000 to $96,0001.35x$56,000
New York, NY$75,000$59,000 to $94,0001.28x$59,000
Honolulu, HI$75,000$60,000 to $95,0001.30x$58,000
Boston, MA$74,000$58,000 to $93,0001.22x$61,000
Washington DC, DC$72,000$57,000 to $90,0001.25x$58,000
Los Angeles, CA$71,000$56,000 to $90,0001.18x$60,000
Seattle, WA$69,000$55,000 to $87,0001.24x$56,000
San Diego, CA$69,000$54,000 to $86,0001.17x$59,000
Houston, TX$54,000$43,000 to $68,0000.97x$56,000

See all 81 cities for Clinical Research Coordinator →

Salary by role in Houston.

Salary comparison by role in Houston
RoleMedianRange
CTO$285,000$222,000 to $371,000
CEO$269,000$196,000 to $372,000
General Counsel$263,000$205,000 to $342,000
Electrician$58,000$46,000 to $77,000
Carpenter$58,000$47,000 to $75,000
Real Estate Agent$58,000$38,000 to $88,000
Clinical Research Coordinator$54,000$43,000 to $68,000
Insurance Agent$54,000$41,000 to $74,000

What you should know.

Before you negotiate a Clinical Research Coordinator offer in Houston, understand the terrain. Houston's economy is deeply rooted in energy, with a growing presence in healthcare, aerospace, and technology. The Texas Medical Center is the world's largest, driving massive demand for clinical and research roles. Houston's low cost of living and no state income tax make it an attractive destination for professionals seeking strong purchasing power. Therapeutic area and trial phase drive the biggest pay differences. Oncology, gene therapy, and Phase I trials pay the most due to protocol complexity. ACRP or SoCRA certification adds 8 to 12% above non-certified coordinators. Academic medical centers and large CROs in biotech hubs offer the highest salaries.

Entry-level CRCs start at $48,000 to $55,000 with a science degree. Certified CRCs with three to five years of experience earn $65,000 to $80,000. Senior CRCs or clinical research managers can reach $85,000 to $110,000 overseeing multi-site trials and regulatory submissions. In Houston, cost of living sits near the national average, so the numbers you see are roughly what you keep.

Base salary is not the full picture. CRCs receive benefits including tuition reimbursement, certification exam fees, and conference attendance stipends. CRO-employed coordinators may receive project completion bonuses of $2,000 to $5,000. Some pharmaceutical sponsors offer annual merit increases of 3 to 6%. And on the tax side: texas has no state income tax, giving Houston workers strong take home pay. The city's overall cost of living is below the national average, further stretching your salary. When someone quotes you $54,000, ask what the total package looks like. The gap between base and total comp is where real money hides.

On negotiation: Emphasize industry specialization in energy or healthcare. Houston employers pay significant premiums for domain expertise in these sectors over generalist candidates. The range for Clinical Research Coordinators in Houston runs from $43,000 to $68,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.

Sources: BLS OES, H-1B LCA (DOL). COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified July 1, 2026. Full methodology

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Is your offer competitive?

Enter your Clinical Research Coordinator offer to see where you stand in Houston.

$

25th

$43,000

Median

$54,000

75th

$68,000

Considering a related role?

  • An Electrician in Houston earns $58,000 (7% more)
  • The highest-paying role in Houston is CTO at $285,000

Common questions.

Yes, certified CRCs earn 8 to 12% more than non-certified peers. Certification demonstrates regulatory knowledge and GCP compliance expertise that sponsors require. It also opens doors to senior coordinator and management roles with substantially higher pay.

Pharma and biotech companies pay CRCs 15 to 25% more than academic medical centers, with salaries of $70,000 to $90,000. However, academic positions offer tuition benefits, publication opportunities, and more predictable schedules that appeal to many coordinators.

The national median for a Clinical Research Coordinator is $55,670. In Houston, cost of living adjustments push the median to $54,000. That discount reflects Houston's lower housing, transportation, and everyday costs.

Houston's economy is deeply rooted in energy, with a growing presence in healthcare, aerospace, and technology. The Texas Medical Center is the world's largest, driving massive demand for clinical and research roles. For Clinical Research Coordinators specifically, therapeutic area and trial phase drive the biggest pay differences, which signals sustained demand. The current compensation range of $43,000 to $68,000 reflects a market that is competing for talent.

Texas has no state income tax, giving Houston workers strong take home pay. The city's overall cost of living is below the national average, further stretching your salary. When comparing offers across states, your take home pay matters more than the number on the offer letter. A lower salary in a no income tax state can net more than a higher one elsewhere.

Clinical Research Coordinator hiring in Houston typically involves three to five rounds: a recruiter screen, a technical or skills assessment, one or two team interviews, and a final conversation with leadership. Companies in Houston's Energy & Oil/Gas sector may add domain specific evaluations. The process usually takes two to four weeks. Prepare by researching the company and practicing with Orbyt's Interview Prep tool.

Clinical Research Coordinator salary in other cities.

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"Clinical Research Coordinator Salary in Houston, TX." Orbyt Salary Explorer, August 2026. https://www.orbytlabs.ai/orbyt-jobs/salaries/clinical-research-coordinator/houston

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