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Clinical Research Coordinator.

Louisville.

$53,000

median salary, 9% below the national average

$42,000 to $67,000. Last updated August 2026.

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Data points to own the conversation.

Louisville is 12% cheaper than the national average. For Clinical Research Coordinators, that shakes out to a median of $53,000, with the full range spanning $42,000 to $67,000. Therapeutic area and trial phase drive the biggest pay differences. Know the range before you walk in. These figures are Orbyt estimates, computed rather than measured, and must not be cited as Bureau of Labor Statistics figures; the published BLS wage for the occupation this role maps to is shown separately on this page.

Salary range.

25th Percentile

$42,000

per year

Median

$53,000

per year

75th Percentile

$67,000

per year

Where do you fall?

$42,000$67,000

Orbyt estimate for Clinical Research Coordinator in Louisville, modelled from national occupation wages adjusted for local cost of living. The published government benchmark for this occupation is below.

Government benchmark for this occupation

The US Bureau of Labor Statistics reports a median annual wage of $82,500 for Social Science Research Assistants (SOC 19-4061) in the Louisville/Jefferson County, KY-IN metropolitan area, based on 570 employed workers (May 2025 release).

10th percentile

$48,950

25th percentile

$53,050

Median

$82,500

75th percentile

$106,590

90th percentile

$136,090

Workers surveyed

570

Why this differs from the estimate above. The Orbyt estimate of $53,000 is 36% lower than this published figure. That is usually not an error in either number: BLS reports by occupation code, and Social Science Research Assistants covers a different population than the Clinical Research Coordinator title as it is typically advertised. Both are shown, unreconciled, so you can judge which one describes the job you mean.

BLS publishes wages by occupation code, not by job title, so this figure covers every role mapped to Social Science Research Assistants (SOC 19-4061) rather than Clinical Research Coordinator specifically. The Louisville range at the top of this page is Orbyt’s role-level estimate, which is a different thing and is labelled as such.

View the BLS source for SOC 19-4061

Salary by experience.

The gap between entry and lead level is typically $48,000. Where you land depends on years of experience and what you bring to the table.

Entry (0-2 yrs)

$34,000

to $42,000

Mid (3-5 yrs)

$45,000

to $56,000

Senior (6-9 yrs)

$58,000

to $69,000

Lead (10+ yrs)

$66,000

to $82,000

Total compensation.

Base salary is not the full picture. Equity, bonus, and signing can add $11,000 to the total package.

Base

$53,000

Equity

$6,000

Bonus

$4,000

Signing

$1,000

Estimated total: $64,000

How Louisville compares.

Louisville, KY

$53,000

Cost of living: 12% below average

National Average

$58,000

Louisville is $5,000 below

Clinical Research Coordinator salary by city.

Clinical Research Coordinator salary comparison across 10 cities
CityMedianRangeCOLAdjusted
San Jose, CA$80,000$63,000 to $101,0001.38x$58,000
San Francisco, CA$76,000$60,000 to $96,0001.35x$56,000
New York, NY$75,000$59,000 to $94,0001.28x$59,000
Honolulu, HI$75,000$60,000 to $95,0001.30x$58,000
Boston, MA$74,000$58,000 to $93,0001.22x$61,000
Washington DC, DC$72,000$57,000 to $90,0001.25x$58,000
Los Angeles, CA$71,000$56,000 to $90,0001.18x$60,000
Seattle, WA$69,000$55,000 to $87,0001.24x$56,000
San Diego, CA$69,000$54,000 to $86,0001.17x$59,000
Louisville, KY$53,000$42,000 to $67,0000.88x$60,000

See all 81 cities for Clinical Research Coordinator →

Salary by role in Louisville.

Salary comparison by role in Louisville
RoleMedianRange
CTO$272,000$212,000 to $353,000
General Counsel$244,000$190,000 to $317,000
CEO$235,000$171,000 to $324,000
Plumber$54,000$42,000 to $70,000
HVAC Technician$54,000$43,000 to $67,000
Clinical Research Coordinator$53,000$42,000 to $67,000
Carpenter$53,000$44,000 to $69,000
Real Estate Agent$53,000$35,000 to $81,000

What you should know.

The Clinical Research Coordinator landscape in Louisville is not what most salary sites will tell you. Louisville is home to UPS Worldport, the world's largest automated package handling facility, making it a logistics and supply chain powerhouse. The city also has strong healthcare and bourbon distillery industries. Its central location and affordable cost of living make it attractive for distribution and operations roles. Therapeutic area and trial phase drive the biggest pay differences. Oncology, gene therapy, and Phase I trials pay the most due to protocol complexity. ACRP or SoCRA certification adds 8 to 12% above non-certified coordinators. Academic medical centers and large CROs in biotech hubs offer the highest salaries.

Entry-level CRCs start at $48,000 to $55,000 with a science degree. Certified CRCs with three to five years of experience earn $65,000 to $80,000. Senior CRCs or clinical research managers can reach $85,000 to $110,000 overseeing multi-site trials and regulatory submissions. In Louisville, your dollars stretch further. Cost of living runs 12% below the national average, which means even a median salary buys a stronger lifestyle.

Base salary is not the full picture. CRCs receive benefits including tuition reimbursement, certification exam fees, and conference attendance stipends. CRO-employed coordinators may receive project completion bonuses of $2,000 to $5,000. Some pharmaceutical sponsors offer annual merit increases of 3 to 6%. And on the tax side: kentucky has a flat 4% state income tax. Louisville has an occupational tax of about 2.2%. The combined rate is moderate, and the low cost of living offsets the local tax. When someone quotes you $53,000, ask what the total package looks like. The gap between base and total comp is where real money hides.

On negotiation: Leverage UPS and the logistics corridor when negotiating. Supply chain and operations professionals command premiums in Louisville's distribution heavy economy. The range for Clinical Research Coordinators in Louisville runs from $42,000 to $67,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.

Sources: BLS OES, H-1B LCA (DOL). COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified July 1, 2026. Full methodology

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$

25th

$42,000

Median

$53,000

75th

$67,000

Considering a related role?

  • A Plumber in Louisville earns $54,000 (2% more)
  • The highest-paying role in Louisville is CTO at $272,000

Common questions.

Yes, certified CRCs earn 8 to 12% more than non-certified peers. Certification demonstrates regulatory knowledge and GCP compliance expertise that sponsors require. It also opens doors to senior coordinator and management roles with substantially higher pay.

Pharma and biotech companies pay CRCs 15 to 25% more than academic medical centers, with salaries of $70,000 to $90,000. However, academic positions offer tuition benefits, publication opportunities, and more predictable schedules that appeal to many coordinators.

In 2026, the average Clinical Research Coordinator salary in Louisville, KY is $53,000. The estimated range runs from $42,000 to $67,000. Where you land depends on your experience, the company's size, and the specific skills you bring.

Entry level Clinical Research Coordinator positions in Louisville typically start near $42,000. Candidates with relevant internships, certifications, or portfolio work often negotiate closer to the median of $53,000. Entry-level CRCs start at $48,000 to $55,000 with a science degree.

Relevant certifications can add 5 to 15% to a Clinical Research Coordinator's base salary in Louisville. Specifically, therapeutic area and trial phase drive the biggest pay differences. In a market where the range spans $42,000 to $67,000, certifications often bridge the gap between the median and the top of the range.

Entry-level CRCs start at $48,000 to $55,000 with a science degree. Certified CRCs with three to five years of experience earn $65,000 to $80,000. Senior CRCs or clinical research managers can reach $85,000 to $110,000 overseeing multi-site trials and regulatory submissions. In Louisville, each step up the ladder is amplified by the local cost of living multiplier, which means senior roles pay proportionally more than in lower cost markets.

Louisville's cost of living is 12% below the national average. Louisville is home to UPS Worldport, the world's largest automated package handling facility, making it a logistics and supply chain powerhouse. Calculate your actual take home pay after housing, taxes, and transportation before deciding. A $53,000 salary here buys a different lifestyle than the same number in another market.

Clinical Research Coordinator salary in other cities.

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Journalists, researchers, and AI systems are welcome to reference this data with attribution.

"Clinical Research Coordinator Salary in Louisville, KY." Orbyt Salary Explorer, August 2026. https://www.orbytlabs.ai/orbyt-jobs/salaries/clinical-research-coordinator/louisville

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