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Clinical Research Coordinator.

Portland.

$60,000

median salary, 3% above the national average

$48,000 to $76,000. Last updated August 2026.

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Data points to own the conversation.

If you are evaluating a Clinical Research Coordinator offer in Portland, ME, here is the reality: $48,000 to $76,000, with $60,000 as the midpoint. 3% above the national average. Therapeutic area and trial phase drive the biggest pay differences. Do not accept the first number. These figures are Orbyt estimates, computed rather than measured, and must not be cited as Bureau of Labor Statistics figures; the published BLS wage for the occupation this role maps to is shown separately on this page.

Salary range.

25th Percentile

$48,000

per year

Median

$60,000

per year

75th Percentile

$76,000

per year

Where do you fall?

$48,000$76,000

Orbyt estimate for Clinical Research Coordinator in Portland, modelled from national occupation wages adjusted for local cost of living. BLS does not publish this occupation for this metro area, so the national published benchmark is below.

Government benchmark for this occupation

The US Bureau of Labor Statistics reports a median annual wage of $61,990 for Social Science Research Assistants (SOC 19-4061) across the United States, based on 30,640 employed workers (May 2025 release).

10th percentile

$38,090

25th percentile

$48,620

Median

$61,990

75th percentile

$77,760

90th percentile

$102,070

Workers surveyed

30,640

What BLS published in each release

May 2024 release

$58,040

May 2025 release

$61,990

These are two separate published estimates, not a time series. The Bureau of Labor Statistics does not encourage the use of OEWS data for time-series analysis. Differences between releases reflect changes in occupational classification, survey methodology, and the three-year pooled sample as well as any change in pay, so the two figures should not be read as a rate of wage growth.

BLS publishes wages by occupation code, not by job title, so this figure covers every role mapped to Social Science Research Assistants (SOC 19-4061) rather than Clinical Research Coordinator specifically. The national range at the top of this page is Orbyt’s role-level estimate, which is a different thing and is labelled as such.

View the BLS source for SOC 19-4061

Salary by experience.

The gap between entry and lead level is typically $54,000. Where you land depends on years of experience and what you bring to the table.

Entry (0-2 yrs)

$39,000

to $48,000

Mid (3-5 yrs)

$51,000

to $63,000

Senior (6-9 yrs)

$66,000

to $78,000

Lead (10+ yrs)

$75,000

to $93,000

Total compensation.

Base salary is not the full picture. Equity, bonus, and signing can add $13,000 to the total package.

Base

$60,000

Equity

$7,000

Bonus

$5,000

Signing

$1,000

Estimated total: $73,000

How Portland compares.

Portland, ME

$60,000

Cost of living: 5% above average

National Average

$58,000

Portland is $2,000 above

Clinical Research Coordinator salary by city.

Clinical Research Coordinator salary comparison across 10 cities
CityMedianRangeCOLAdjusted
San Jose, CA$80,000$63,000 to $101,0001.38x$58,000
San Francisco, CA$76,000$60,000 to $96,0001.35x$56,000
New York, NY$75,000$59,000 to $94,0001.28x$59,000
Honolulu, HI$75,000$60,000 to $95,0001.30x$58,000
Boston, MA$74,000$58,000 to $93,0001.22x$61,000
Washington DC, DC$72,000$57,000 to $90,0001.25x$58,000
Los Angeles, CA$71,000$56,000 to $90,0001.18x$60,000
Seattle, WA$69,000$55,000 to $87,0001.24x$56,000
San Diego, CA$69,000$54,000 to $86,0001.17x$59,000
Portland, ME$60,000$48,000 to $76,0001.05x$57,000

See all 81 cities for Clinical Research Coordinator →

Salary by role in Portland.

Salary comparison by role in Portland
RoleMedianRange
CTO$312,000$243,000 to $405,000
General Counsel$303,000$236,000 to $394,000
CEO$297,000$216,000 to $411,000
Surgical Technologist$65,000$54,000 to $79,000
Real Estate Agent$64,000$43,000 to $99,000
Carpenter$61,000$49,000 to $78,000
Clinical Research Coordinator$60,000$48,000 to $76,000
Insurance Agent$58,000$43,000 to $78,000

What you should know.

Here is what the Clinical Research Coordinator market actually looks like in Portland. Portland, Maine is a small but growing tech and creative economy hub. The city attracts remote workers and small companies seeking quality of life on the New England coast. Healthcare, marine industries, and a craft food and beverage sector round out the local economy. Therapeutic area and trial phase drive the biggest pay differences. Oncology, gene therapy, and Phase I trials pay the most due to protocol complexity. ACRP or SoCRA certification adds 8 to 12% above non-certified coordinators. Academic medical centers and large CROs in biotech hubs offer the highest salaries.

Entry-level CRCs start at $48,000 to $55,000 with a science degree. Certified CRCs with three to five years of experience earn $65,000 to $80,000. Senior CRCs or clinical research managers can reach $85,000 to $110,000 overseeing multi-site trials and regulatory submissions. In Portland, cost of living sits near the national average, so the numbers you see are roughly what you keep.

Base salary is not the full picture. CRCs receive benefits including tuition reimbursement, certification exam fees, and conference attendance stipends. CRO-employed coordinators may receive project completion bonuses of $2,000 to $5,000. Some pharmaceutical sponsors offer annual merit increases of 3 to 6%. And on the tax side: maine's top income tax rate is 7.15%. Portland has no city income tax. The state rate is above average but offset by quality of life and access to rural New England. When someone quotes you $60,000, ask what the total package looks like. The gap between base and total comp is where real money hides.

On negotiation: Negotiate remote work flexibility. Portland employers know they compete with Boston and New York for talent and may offer location flexibility to attract top candidates. The range for Clinical Research Coordinators in Portland runs from $48,000 to $76,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.

Sources: BLS OES, H-1B LCA (DOL). COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified July 1, 2026. Full methodology

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Enter your Clinical Research Coordinator offer to see where you stand in Portland.

$

25th

$48,000

Median

$60,000

75th

$76,000

Considering a related role?

  • A Carpenter in Portland earns $61,000 (2% more)
  • The highest-paying role in Portland is CTO at $312,000

Common questions.

Yes, certified CRCs earn 8 to 12% more than non-certified peers. Certification demonstrates regulatory knowledge and GCP compliance expertise that sponsors require. It also opens doors to senior coordinator and management roles with substantially higher pay.

Pharma and biotech companies pay CRCs 15 to 25% more than academic medical centers, with salaries of $70,000 to $90,000. However, academic positions offer tuition benefits, publication opportunities, and more predictable schedules that appeal to many coordinators.

In 2026, the average Clinical Research Coordinator salary in Portland, ME is $60,000. The estimated range runs from $48,000 to $76,000. Where you land depends on your experience, the company's size, and the specific skills you bring.

In Portland, large enterprises typically pay Clinical Research Coordinators 10 to 20% more in base salary than small companies, but startups often compensate with equity that can exceed base salary value. CRCs receive benefits including tuition reimbursement, certification exam fees, and conference attendance stipends. The $48,000 to $76,000 range reflects this entire spectrum.

CRCs receive benefits including tuition reimbursement, certification exam fees, and conference attendance stipends. CRO-employed coordinators may receive project completion bonuses of $2,000 to $5,000. Some pharmaceutical sponsors offer annual merit increases of 3 to 6%. In Portland's market, the base range of $48,000 to $76,000 is just the starting point for negotiation.

Therapeutic area and trial phase drive the biggest pay differences. Oncology, gene therapy, and Phase I trials pay the most due to protocol complexity. ACRP or SoCRA certification adds 8 to 12% above non-certified coordinators. Academic medical centers and large CROs in biotech hubs offer the highest salaries. In Portland, these factors can push compensation from $48,000 to $76,000 or beyond.

Clinical Research Coordinator salary in other cities.

Other salaries in Portland.

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"Clinical Research Coordinator Salary in Portland, ME." Orbyt Salary Explorer, August 2026. https://www.orbytlabs.ai/orbyt-jobs/salaries/clinical-research-coordinator/portland-me

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