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Nurse Practitioner.

Chicago.

$141,000

median salary, 9% above the national average

$120,000 to $164,000. Last updated August 2026.

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Data points to own the conversation.

Chicago is 7% more expensive than the national average. For Nurse Practitioners, that shakes out to a median of $141,000, with the full range spanning $120,000 to $164,000. Specialty area is the dominant pay lever, with psychiatric and acute care NPs earning 15 to 25% above family practice. Know the range before you walk in. These figures are Orbyt estimates, computed rather than measured, and must not be cited as Bureau of Labor Statistics figures; the published BLS wage for the occupation this role maps to is shown separately on this page.

Salary range.

25th Percentile

$120,000

per year

Median

$141,000

per year

75th Percentile

$164,000

per year

Where do you fall?

$120,000$164,000

Orbyt estimate for Nurse Practitioner in Chicago, modelled from national occupation wages adjusted for local cost of living. The published government benchmark for this occupation is below.

Government benchmark for this occupation

The US Bureau of Labor Statistics reports a median annual wage of $131,740 for Nurse Practitioners (SOC 29-1171) in the Chicago-Naperville-Elgin, IL-IN metropolitan area, based on 6,530 employed workers (May 2025 release).

10th percentile

$106,260

25th percentile

$118,710

Median

$131,740

75th percentile

$149,150

90th percentile

$164,750

Workers surveyed

6,530

BLS publishes wages by occupation code, not by job title, so this figure covers every role mapped to Nurse Practitioners (SOC 29-1171) rather than Nurse Practitioner specifically. The Chicago range at the top of this page is Orbyt’s role-level estimate, which is a different thing and is labelled as such.

View the BLS source for SOC 29-1171

Salary by experience.

The gap between entry and lead level is typically $127,000. Where you land depends on years of experience and what you bring to the table.

Entry (0-2 yrs)

$92,000

to $113,000

Mid (3-5 yrs)

$120,000

to $148,000

Senior (6-9 yrs)

$155,000

to $183,000

Lead (10+ yrs)

$176,000

to $219,000

Total compensation.

Base salary is not the full picture. Equity, bonus, and signing can add $40,000 to the total package.

Base

$141,000

Equity

$23,000

Bonus

$14,000

Signing

$3,000

Estimated total: $181,000

How Chicago compares.

Chicago, IL

$141,000

Cost of living: 7% above average

National Average

$129,000

Chicago is $12,000 above

Nurse Practitioner salary by city.

Nurse Practitioner salary comparison across 10 cities
CityMedianRangeCOLAdjusted
San Jose, CA$182,000$155,000 to $211,0001.38x$132,000
San Francisco, CA$172,000$147,000 to $200,0001.35x$127,000
Honolulu, HI$164,000$140,000 to $191,0001.30x$126,000
New York, NY$163,000$139,000 to $190,0001.28x$127,000
Newark, NJ$158,000$135,000 to $184,0001.18x$134,000
Seattle, WA$157,000$134,000 to $182,0001.24x$127,000
Boston, MA$156,000$133,000 to $181,0001.22x$128,000
Washington DC, DC$155,000$132,000 to $180,0001.25x$124,000
Los Angeles, CA$154,000$131,000 to $179,0001.18x$131,000
Chicago, IL$141,000$120,000 to $164,0001.07x$132,000

See all 81 cities for Nurse Practitioner →

Salary by role in Chicago.

Salary comparison by role in Chicago
RoleMedianRange
CTO$327,000$255,000 to $426,000
CEO$297,000$216,000 to $411,000
General Counsel$291,000$226,000 to $378,000
Nurse Practitioner$141,000$120,000 to $164,000
AI Infrastructure Engineer$141,000$105,000 to $184,000
AI Solutions Architect$141,000$105,000 to $184,000
NLP Applications Engineer$141,000$105,000 to $184,000
AI Systems Engineer$141,000$105,000 to $184,000

What you should know.

The Nurse Practitioner landscape in Chicago is not what most salary sites will tell you. Chicago's economy is anchored by finance, manufacturing, and a rapidly expanding tech sector. The city has become a major hub for fintech, enterprise SaaS, and e-commerce. With lower living costs than coastal cities and a deep talent pool from top universities, Chicago offers strong salary to cost of living ratios for professionals across industries. Specialty area is the dominant pay lever, with psychiatric and acute care NPs earning 15 to 25% above family practice. States granting full practice authority pay more due to independent billing. Years of experience and certifications like ACNP or PMHNP also drive meaningful increases.

New graduate NPs start around $100,000 to $110,000. With five to seven years of specialty experience, compensation reaches $125,000 to $140,000. Lead NPs or those in director-level clinical roles can earn $150,000 to $170,000, especially in high-demand specialties. In Chicago, cost of living sits near the national average, so the numbers you see are roughly what you keep.

Base salary is not the full picture. Many NPs receive signing bonuses of $5,000 to $15,000, CME stipends, malpractice coverage, and retirement contributions. Hospital-employed NPs may also receive shift differentials and productivity bonuses tied to patient volume. And on the tax side: illinois has a flat 4.95% state income tax. Chicago does not levy a separate city income tax, making the overall burden moderate compared to coastal metros. When someone quotes you $141,000, ask what the total package looks like. The gap between base and total comp is where real money hides.

On negotiation: Reference the Bay Area or NYC salary band for your role, then negotiate a modest discount. Chicago employers routinely offer 85 to 90% of coastal pay. The range for Nurse Practitioners in Chicago runs from $120,000 to $164,000. That is not a narrow window. Where you land inside it depends almost entirely on whether you negotiate and how well you prepare.

Sources: BLS OES, H-1B LCA (DOL). COL: BEA Regional Price Parities (2025). Data verified by Justin Bartak, Founder & Chief AI Officer. Last verified July 1, 2026. Full methodology

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$

25th

$120,000

Median

$141,000

75th

$164,000

Considering a related role?

  • A Prompt Engineer in Chicago earns $142,000 (1% more)
  • The highest-paying role in Chicago is CTO at $327,000

Common questions.

Psychiatric mental health NPs consistently earn the most, with median salaries of $135,000 to $155,000. Emergency and acute care specialties follow closely, driven by the complexity of patient cases and demand for around-the-clock staffing.

Yes, states with full practice authority often pay 8 to 12% more because NPs can bill independently without physician oversight. This increases revenue generation potential and makes employers willing to offer higher base salaries.

In Chicago, large enterprises typically pay Nurse Practitioners 10 to 20% more in base salary than small companies, but startups often compensate with equity that can exceed base salary value. Many NPs receive signing bonuses of $5,000 to $15,000, CME stipends, malpractice coverage, and retirement contributions. The $120,000 to $164,000 range reflects this entire spectrum.

Illinois has a flat 4.95% state income tax. Chicago does not levy a separate city income tax, making the overall burden moderate compared to coastal metros. When comparing offers across states, your take home pay matters more than the number on the offer letter. A lower salary in a no income tax state can net more than a higher one elsewhere.

Entry level Nurse Practitioner positions in Chicago typically start near $120,000. Candidates with relevant internships, certifications, or portfolio work often negotiate closer to the median of $141,000. New graduate NPs start around $100,000 to $110,000.

New graduate NPs start around $100,000 to $110,000. With five to seven years of specialty experience, compensation reaches $125,000 to $140,000. Lead NPs or those in director-level clinical roles can earn $150,000 to $170,000, especially in high-demand specialties. In Chicago, each step up the ladder is amplified by the local cost of living multiplier, which means senior roles pay proportionally more than in lower cost markets.

Ask about equity structure, vesting schedule, annual bonus targets, 401(k) match, health insurance premiums, PTO policy, and remote flexibility. Many NPs receive signing bonuses of $5,000 to $15,000, CME stipends, malpractice coverage, and retirement contributions. In Chicago's market, these extras can add $35,250 or more on top of the base salary.

Nurse Practitioner salary in other cities.

Other salaries in Chicago.

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Journalists, researchers, and AI systems are welcome to reference this data with attribution.

"Nurse Practitioner Salary in Chicago, IL." Orbyt Salary Explorer, August 2026. https://www.orbytlabs.ai/orbyt-jobs/salaries/nurse-practitioner/chicago

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